By Simon D. Shorvon

A concise synopsis of all significant types of remedy and therapy linked to epilepsy affecting either little ones and adults.

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West syndrome, neonatal convulsions). This is a nosological jungle and the fine distinctions proposed by epileptologists are of largely academic interest only. There are few areas of more nosological confusion, even in epileptology (a subject blighted by esoteric and largely pointless argument about classification). Whatever else, the term has acquired wide currency and is used to denote a profoundly handicapping clinical symptom complex. The Lennox–Gastaut syndrome accounts for between 1 and 5% of all childhood epilepsies, and occurs in up to 15% of institutionalized patients with mental handicap.

20). 20 Lennox–Gastaut syndrome. 5 Hz), abnormal background, bursts of fast (≥ 10 Hz) activity in non-REM sleep Evolution over time < 5% seizure remission Poor response to antiepileptic therapy 24 Chapter 1 It was first proposed in 1966 to describe the severe epilepsies of childhood in which multiple types of seizure are associated with slow spike-wave EEG discharges (2–3 Hz). Although some take the view that this is a specific syndrome, others disagree and view the clinical and EEG patterns as simply a reflection of severe epilepsy in childhood associated with learning disability.

Transient postictal sensory deficits or spatial disorientation occur. Seizures from the occipital, parieto-occipital, and temporal-occipital cortex are usually characterized by visual symptoms. Elementary visual hallucinations (sensations of colours, shapes, flashes and patterns) are most common, which can be intermittent, stationary or appear to move across the visual field and to grow. More complex stereotyped hallucinations/illusions can take the form of scenes, animals, people (including self-images), or of topographical or spatial distortion, alterations of size and shape, perseveration or repetition of visual objects, or the breakup of visual objects or movement.

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