By Ekaterina Kulakovskaya, Tatiana Kulakovskaya
Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects presents a entire view of the biochemistry, organic task, and sensible program of extracellular glycolipids of yeast. This booklet brings much-needed readability to the complicated subject of glycolipids and streamlines the relatively complicated terminology used for glycolipids. It additionally offers a wealth of contemporary information on their composition, constitution and homes, biosynthetic pathways, tools of isolation and identity, antifungal task, and mechanisms of action.
Studies of extracellular glycolipids of yeast now draw the eye of researchers in existence technological know-how and biotechnology because of a variety of lately printed organic houses of those compounds. those compounds are scientifically and essentially promising in drugs and agriculture because of their biosurfactant and fungicidal houses, in addition to a couple of different organic actions. Extracellular Glycolipids of Yeasts offers researchers learning biochemistry of microorganisms and comparable biologically energetic compounds a much-needed consultant to the fundamental facts that would relief in those more and more generative pursuits.
- Provides a transparent assessment of the fundamental info on yeast biosurfactants utilizing an easy survey-style approach
- Delivers accomplished view of biochemistry, organic task, and useful software of yeasts to assist of their medical and useful use
- Clarifies and simplifies the advanced subject of glycolipids, and its often-confusing terminology
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Extra info for Extracellular Glycolipids of Yeasts. Biodiversity, Biochemistry, and Prospects
2012). We have checked how glucose influences the sensitivity to cellobiose lipids. The sensitivity of S. cerevisiae cells to cellobiose lipid increased on addition of glucose to the incubation medium. , 2008a). 9). We also compared the effect of cellobiose lipid on the cells of S. cerevisiae with different polyphosphate content. Simultaneously, we compared the effects of silver ions and the known anionic detergent SDS on the above cells. The cells of S. , 1996). , 2011) showed that the sensitivity to the cellobiose lipid of Ps.
However, the antibiotic activity was low. The new interest in the study of antifungal properties of extracellular glycolipids emerged in 1994, when Cr. humicola was shown to have a low-molecular protease-insensitive antifungal agent secreted into the liquid medium and inhibiting the growth of various species of yeast and fungi (Golubev and Shabalin, 1994). The antifungal activity manifested only at acidic pH. 1) allows the screening of promising producers. 1 shows the results of such testing. By this approach it was shown that Cr.
0. 04 mg/ml, while in Gramnegative species it is higher by an order of magnitude. The authors explain this effect by different membrane structures of Gram-positive and Gram-negative bacteria. Moreover, they believe that flocculosin, even though having a fungicidal effect on yeasts, exerts only a bacteriostatic effect on the cells of Staphylococcus aureus. It is important to note that the glycolipid was not toxic for the human cell lines used by the authors even at the 10- and 100-fold higher concentrations than those inhibiting the growth of C.